Requirement for cyclin D3 in germinal center formation and function

Germinal Centers (GC) of secondary lymphoid tissues are critical to mounting a high-affinity humoral immune response. B cells within the GC undergo rapid clonal expansion and selection while diversifying their antibody genes. Although it is generally believed that GC B cells employ a unique prolifer...

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Hauptverfasser: Peled, Jonathan U., Yu, J. Jessica, Venkatesh, Jeganathan, Bi, Enguang, Ding, B. Belinda, Krupski-Downs, Melissa, Shaknovich, Rita, Sicinski, Piotr, Diamond, Betty, Scharff, Matthew D., Ye, B. Hilda
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997820/
https://ncbi.nlm.nih.gov/pubmed/20404856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2010.55
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