Atorvastatin Improves Survival in Septic Rats: Effect on Tissue Inflammatory Pathway and on Insulin Signaling

The aim of the present study was to investigate whether the survival-improving effect of atorvastatin in sepsis is accompanied by a reduction in tissue activation of inflammatory pathways and, in parallel, an improvement in tissue insulin signaling in rats. Diffuse sepsis was induced by cecal ligati...

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Main Authors: Calisto, Kelly Lima, Carvalho, Bruno de Melo, Ropelle, Eduardo Rochete, Mittestainer, Francine Cappa, Camacho, Angélica Costa Aranha, Guadagnini, Dioze, Carvalheira, José Barreto Campelo, Saad, Mario José Abdalla
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997789/
https://ncbi.nlm.nih.gov/pubmed/21151908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014232
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