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A Simple Method for C-6 Modification of Guanine Nucleosides

A facile method for the introduction of various substituents at the C-6 position of guanosine and 2′-deoxyguanosine is reported. In a simple, 1-step transformation, tert-butyldimethylsilyl protected guanosine and 2′-deoxyguanosine were converted to the O(6)-(benzotriazol-1-yl) derivatives via reacti...

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Detalhes bibliográficos
Main Authors: Lakshman, Mahesh K., Frank, Josh
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997774/
https://ncbi.nlm.nih.gov/pubmed/19582304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b905298d
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