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Assigning Significance in Label-Free Quantitative Proteomics to Include Single-Peptide-Hit Proteins with Low Replicates

When sample replicates are limited in a label-free proteomics experiment, selecting differentially regulated proteins with an assignment of statistical significance remains difficult for proteins with a single-peptide hit or a small fold-change. This paper aims to address this issue. An important co...

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Detalhes bibliográficos
Autor principal: Li, Qingbo
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997754/
https://ncbi.nlm.nih.gov/pubmed/21152383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/731582
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