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Determination of the substrate-docking site of protein tyrosine kinase C-terminal Src kinase

Protein tyrosine kinases (PTK) are key enzymes of mammalian signal transduction. For the fidelity of signal transduction, each PTK phosphorylates only one or a few proteins on specific Tyr residues. Substrate specificity is thought to be mediated by PTK–substrate docking interactions and recognition...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lee, Sungsoo, Lin, Xiaofeng, Nam, Nguyen Hai, Parang, Keykavous, Sun, Gongqin
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299771/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14657361/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2534493100
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