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Histone Deacetylase Inhibitors: The Epigenetic Therapeutics That Repress Hypoxia-Inducible Factors

Histone deacetylase inhibitors (HDACIs) have been actively explored as a new generation of chemotherapeutics for cancers, generally known as epigenetic therapeutics. Recent findings indicate that several types of HDACIs repress angiogenesis, a process essential for tumor metabolism and progression....

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Bibliografske podrobnosti
Main Authors: Chen, Shuyang, Sang, Nianli
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997513/
https://ncbi.nlm.nih.gov/pubmed/21151670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/197946
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