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IFN-γ acts as anti-angiogenic cytokine in the human cornea by regulating the expression of VEGF-A and sVEGF-R1

Inflammatory processes within the cornea are known to be associated with corneal neovascularization (CN). We examined the effects of inflammatory mediators on the expression of angiogenic factors by corneal cells. TNF-α and IL-1 induced VEGF-A secretion by corneal fibroblasts (HCRF) and this was inh...

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Detalhes bibliográficos
Main Authors: Kommineni, Vijay K., Nagineni, Chandrasekharam N., William, Abitha, Detrick, Barbara, Hooks, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997485/
https://ncbi.nlm.nih.gov/pubmed/18639520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.07.042
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