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Abnormal motor cortex plasticity in premanifest and very early manifest Huntington's disease

BACKGROUND: Cognition is affected early in Huntington's disease, and in HD animal models there is evidence that this reflects abnormal synaptic plasticity. We investigated whether there is evidence for abnormal synaptic plasticity using the human motor cortex-rTMS model, and if so, if there is...

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Autors principals: Orth, M, Schippling, S, Schneider, SA, Bhatia, KP, Talelli, P, Tabrizi, SJ, Rothwell, JC
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997479/
https://ncbi.nlm.nih.gov/pubmed/19828482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.2009.171926
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