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A microfluidic model for single-cell capillary obstruction by Plasmodium falciparum-infected erythrocytes

Severe malaria by Plasmodium falciparum is a potentially fatal disease, frequently unresponsive to even the most aggressive treatments. Host organ failure is associated with acquired rigidity of infected red blood cells and capillary blockage. In vitro techniques have played an important role in mod...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Shelby, J. Patrick, White, John, Ganesan, Karthikeyan, Rathod, Pradipsinh K., Chiu, Daniel T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2003
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Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299747/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14638939/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2433968100
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