Wnt/β-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4

Loss- and gain-of function approaches modulating canonical Wnt/β-catenin activity have established a role for the Wnt/β-catenin pathway during tooth development. Here we show that Wnt/β-catenin signaling is required in the dental mesenchyme for normal incisor development, as locally restricted genet...

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Main Authors: Fujimori, Sayumi, Novak, Hermann, Weissenböck, Martina, Jussila, Maria, Gonçalves, Alexandre, Zeller, Rolf, Galloway, Jenna, Thesleff, Irma, Hartmann, Christine
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997430/
https://ncbi.nlm.nih.gov/pubmed/20883686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.09.009
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