Neurons Preferentially Respond to Self-MHC Class I Allele Products Regardless of Peptide Presented

Studies of mice lacking MHC class I (MHC I)-associated proteins have demonstrated a role for MHC I in neurodevelopment. A central question arising from these observations is whether neuronal recognition of MHC I has specificity for the MHC I allele product and the peptide presented. Using a well-est...

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Detalhes bibliográficos
Main Authors: Escande-Beillard, Nathalie, Washburn, Lorraine, Zekzer, Dan, Wu, Zhongqi-Phyllis, Eitan, Shoshy, Ivkovic, Sonja, Lu, Yuxin, Dang, Hoa, Middleton, Blake, Bilousova, Tina V., Yoshimura, Yoshitaka, Evans, Christopher J., Joyce, Sebastian, Tian, Jide, Kaufman, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997386/
https://ncbi.nlm.nih.gov/pubmed/20018625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902159
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