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Post-formulation peptide drug loading of nanostructures for metered control of NF-κB signaling
The NF-κB signaling pathway is an attractive therapeutic target for cancer and chronic inflammatory diseases. In this study, we report the first strategy to achieve NF-κB inhibition with a peptide inhibitor loaded into perfluorocarbon nanoparticles with the use of a simple post-formulation mixing ap...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2997356/ https://ncbi.nlm.nih.gov/pubmed/20864161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2010.08.080 |
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