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Identification, purification, and characterization of a mast cell-associated cytolytic factor related to tumor necrosis factor.

The role of mast cells and mast-cell-derived factors in natural cytotoxic reactions was investigated. Cultured and freshly isolated murine mast cells are shown to be cytotoxic to WEHI-164 and YAC-1 targets in 18-hr viability assays but not in 4-hr assays. Here, we describe a cytotoxic factor in muri...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Young, J D, Liu, C C, Butler, G, Cohn, Z A, Galli, S J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299715/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3321069/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.24.9175
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