Epigenetic Silencing of Peroxisome Proliferator-Activated Receptor γ Is a Biomarker for Colorectal Cancer Progression and Adverse Patients' Outcome

The relationship between peroxisome proliferator-activated receptor γ (PPARG) expression and epigenetic changes occurring in colorectal-cancer pathogenesis is largely unknown. We investigated whether PPARG is epigenetically regulated in colorectal cancer (CRC) progression. PPARG expression was asses...

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Hauptverfasser: Pancione, Massimo, Sabatino, Lina, Fucci, Alessandra, Carafa, Vincenzo, Nebbioso, Angela, Forte, Nicola, Febbraro, Antonio, Parente, Domenico, Ambrosino, Concetta, Normanno, Nicola, Altucci, Lucia, Colantuoni, Vittorio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997072/
https://ncbi.nlm.nih.gov/pubmed/21151932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014229
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