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Close linkage of the mouse and human CD3 gamma- and delta-chain genes suggests that their transcription is controlled by common regulatory elements.

Antigen receptors on the T-cell surface are noncovalently associated with at least four invariant polypeptide chains, CD3-gamma, -delta, -epsilon, and -zeta. The mouse CD3-gamma gene, consisting of seven exons, was found to be highly homologous to the CD3-delta gene described earlier. Both the high...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Saito, H, Koyama, T, Georgopoulos, K, Clevers, H, Haser, W G, LeBien, T, Tonegawa, S, Terhorst, C
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1987
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299706/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2827170/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.24.9131
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