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Aquaporin 5 Polymorphisms and Rate of Lung Function Decline in Chronic Obstructive Pulmonary Disease

RATIONALE: Aquaporin-5 (AQP5) can cause mucus overproduction and lower lung function. Genetic variants in the AQP5 gene might be associated with rate of lung function decline in chronic obstructive pulmonary disease (COPD). METHODS: Five single nucleotide polymorphisms (SNPs) in AQP5 were genotyped...

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Autori principali: Hansel, Nadia N., Sidhaye, Venkataramana, Rafaels, Nicholas M., Gao, Li, Gao, Peisong, Williams, Renaldo, Connett, John E., Beaty, Terri H., Mathias, Rasika A., Wise, Robert A., King, Landon S., Barnes, Kathleen C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997058/
https://ncbi.nlm.nih.gov/pubmed/21151978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014226
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