Genome-wide conserved consensus transcription factor binding motifs are hyper-methylated

BACKGROUND: DNA methylation can regulate gene expression by modulating the interaction between DNA and proteins or protein complexes. Conserved consensus motifs exist across the human genome ("predicted transcription factor binding sites": "predicted TFBS") but the large majority...

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Autors principals: Choy, Mun-Kit, Movassagh, Mehregan, Goh, Hock-Guan, Bennett, Martin R, Down, Thomas A, Foo, Roger SY
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997012/
https://ncbi.nlm.nih.gov/pubmed/20875111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-519
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