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Comparative genomics reveals a functional thyroid-specific element in the far upstream region of the PAX8 gene

BACKGROUND: The molecular mechanisms leading to a fully differentiated thyrocite are still object of intense study even if it is well known that thyroglobulin, thyroperoxidase, NIS and TSHr are the marker genes of thyroid differentiation. It is also well known that Pax8, TTF-1, Foxe1 and Hhex are th...

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Détails bibliographiques
Auteurs principaux: Nitsch, Roberto, Di Dato, Valeria, di Gennaro, Alessandra, de Cristofaro, Tiziana, Abbondante, Serena, De Felice, Mario, Zannini, Mariastella, Di Lauro, Roberto
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996967/
https://ncbi.nlm.nih.gov/pubmed/20470391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-306
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