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Copy number variation at leptin receptor gene locus associated with metabolic traits and the risk of type 2 diabetes mellitus

BACKGROUND: Recent efforts have been made to link complex human traits and disease susceptibility to DNA copy numbers. The leptin receptor (LEPR) has been implicated in obesity and diabetes. Mutations and genetic variations of LEPR gene have been discovered in rodents and humans. However, the associ...

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Autors principals: Jeon, Jae-Pil, Shim, Sung-Mi, Nam, Hye-Young, Ryu, Gil-Mi, Hong, Eun-Jung, Kim, Hyung-Lae, Han, Bok-Ghee
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996954/
https://ncbi.nlm.nih.gov/pubmed/20624279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-426
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