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Hetero-oligomeric interactions of an ELOVL4 mutant protein: implications in the molecular mechanism of Stargardt-3 macular dystrophy

PURPOSE: Stargardt disease 3 (STGD3) is a juvenile macular dystrophy caused by mutations in the elongase of very long-chain fatty acids-like 4 (ELOVL4) gene, which encodes an elongase involved in the production of extremely long-chain fatty acids. The STGD3-related mutations cause production of C-te...

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Autori principali: Okuda, Ayaka, Naganuma, Tatsuro, Ohno, Yusuke, Abe, Kensuke, Yamagata, Maki, Igarashi, Yasuyuki, Kihara, Akio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Molecular Vision 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996883/
https://ncbi.nlm.nih.gov/pubmed/21139992
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