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Expression of yeast DNA topoisomerase I can complement a conditional-lethal DNA topoisomerase I mutation in Escherichia coli.

We show that, despite differences in primary structure, substrate preference, and mechanism of catalysis, yeast DNA topoisomerase I can functionally substitute for Escherichia coli DNA topoisomerase I. A family of plasmids expressing the yeast TOP1 gene or 5'-deletion mutations of it were used...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Bjornsti, M A, Wang, J C
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1987
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299673/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2827163/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.24.8971
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