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Sequence-specific assembly of FtsK hexamers establishes directional translocation on DNA

FtsK is a homohexameric, RecA-like dsDNA translocase that plays a key role in bacterial chromosome segregation. The FtsK regulatory γ-subdomain determines directionality of translocation through its interaction with specific 8 base pair chromosomal sequences [(KOPS); FtsK Orienting / Polarizing Sequ...

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Detalhes bibliográficos
Main Authors: Graham, James E., Sherratt, David J., Szczelkun, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996697/
https://ncbi.nlm.nih.gov/pubmed/21048089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007518107
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