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Inversin relays Frizzled-8 signals to promote proximal pronephros development
Mutations of inversin cause type II nephronophthisis, an infantile autosomal recessive disease characterized by cystic kidney disease and developmental defects. Inversin regulates Wnt signaling and is required for convergent extension movements during early embryogenesis. We now show that Inversin i...
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Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
National Academy of Sciences
2010
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996658/ https://ncbi.nlm.nih.gov/pubmed/21059920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013070107 |
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