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Dynamics of α-helical subdomain rotation in the intact maltose ATP-binding cassette transporter

ATP-binding cassette (ABC) transporters are powered by a nucleotide-binding domain dimer that opens and closes during cycles of ATP hydrolysis. These domains consist of a RecA-like subdomain and an α-helical subdomain that is specific to the family. Many studies on isolated domains suggest that the...

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Detalhes bibliográficos
Main Authors: Orelle, Cédric, Alvarez, Frances Joan D., Oldham, Michael L., Orelle, Arnaud, Wiley, Theodore E., Chen, Jue, Davidson, Amy L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996640/
https://ncbi.nlm.nih.gov/pubmed/21059948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006544107
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