Spontaneous mutagenesis and oxidative damage to DNA in Salmonella typhimurium.

Salmonella typhimurium strains containing deletions of oxyR, a positive regulator of defenses against oxidative stress, show 10- to 55-fold higher frequencies of spontaneous mutagenesis compared to otherwise isogenic oxyR+ control strains. The high spontaneous-mutation frequency in oxyR deletion str...

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Main Authors: Storz, G, Christman, M F, Sies, H, Ames, B N
Format: Artigo
Sprog:Inglês
Udgivet: 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC299662/
https://ncbi.nlm.nih.gov/pubmed/3321061
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