Impact of Fli-1 transcription factor on autoantibody and lupus nephritis in NZM2410 mice

The transcription factor Fli-1 is implicated in the pathogenesis of both murine and human lupus. Increased levels of Fli-1 mRNA were present in the peripheral blood lymphocytes from lupus patients; furthermore, transgenic overexpression of Fli-1 in normal mice resulted in the development of a lupus-...

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Detalhes bibliográficos
Main Authors: Mathenia, J, Reyes-Cortes, E, Williams, S, Molano, I, Ruiz, P, Watson, D K, Gilkeson, G S, Zhang, X K
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Animal Models
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996603/
https://ncbi.nlm.nih.gov/pubmed/20731671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2010.04245.x
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