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Expression of a synthetic bovine rhodopsin gene in monkey kidney cells.

We report here the high-level expression of a synthetic gene for bovine rhodopsin in transfected monkey kidney COS-1 cells. Rhodopsin is produced in these cells to a level of 0.3% of the cell protein, and it binds exogenously added 11-cis-retinal to generate the characteristic rhodopsin absorption s...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Oprian, D D, Molday, R S, Kaufman, R J, Khorana, H G
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1987
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299653/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2962193/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.24.8874
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