Single secretory granules of live cells recruit syntaxin-1 and synaptosomal associated protein 25 (SNAP-25) in large copy numbers

Before secretory vesicles undergo exocytosis, they must recruit the proteins syntaxin-1 and synaptosomal associated protein 25 (SNAP-25) in the plasma membrane. GFP-labeled versions of both proteins cluster at sites where secretory granules have docked. Single-particle tracking shows that minority p...

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Main Authors: Knowles, M. K., Barg, S., Wan, L., Midorikawa, M., Chen, X., Almers, Wolfhard
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996426/
https://ncbi.nlm.nih.gov/pubmed/21076040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014840107
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