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Comparative expression pattern of Matrix-Metalloproteinases in human glioblastoma cell-lines and primary cultures

BACKGROUND: Glioblastomas (GBM), the most frequent malignant brain tumors in adults, are characterized by an aggressive local growth pattern and highly invasive tumor cells. This invasion is facilitated by expression of matrix metalloproteinases (MMPs), a family of zinc-dependent endopeptidases. The...

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Bibliographische Detailangaben
Hauptverfasser: Hagemann, Carsten, Anacker, Jelena, Haas, Stefanie, Riesner, Daniela, Schömig, Beate, Ernestus, Ralf-Ingo, Vince, Giles H
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996401/
https://ncbi.nlm.nih.gov/pubmed/21067565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-3-293
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