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ZNF217 confers resistance to the pro-apoptotic signals of paclitaxel and aberrant expression of Aurora-A in breast cancer cells

BACKGROUND: ZNF217 is a candidate oncogene located at 20q13, a chromosomal region frequently amplified in breast cancers. The precise mechanisms involved in ZNF217 pro-survival function are currently unknown, and utmost importance is given to deciphering the role of ZNF217 in cancer therapy response...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Thollet, Aurélie, Vendrell, Julie A, Payen, Léa, Ghayad, Sandra E, Ben Larbi, Sabrina, Grisard, Evelyne, Collins, Colin, Villedieu, Marie, Cohen, Pascale A
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996367/
https://ncbi.nlm.nih.gov/pubmed/21059223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-291
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