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Three-dimensional model of the active site of the self-splicing rRNA precursor of Tetrahymena.

The rRNA intervening sequence of Tetrahymena is a catalytic RNA molecule, or "ribozyme." A tertiary-structure model of the active site of this ribozyme has been constructed based on comparative sequence analysis of related group I intervening sequences, data on the accessibility of each nucleotide t...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Kim, S H, Cech, T R
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1987
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299635/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3480510/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.24.8788
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