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An acidic environment changes cyclin D1 localization and alters colony forming ability in gliomas

The human glioma cell lines, U87 and T98G, were evaluated for their ability to survive and form colonies in an acidic environment of pH(ext) 6.0. In contrast to U87, which showed an 80–90% survival rate, only 40% of T98G cells survived 6 days at pH(ext) 6.0 and lost their colony forming ability when...

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Main Authors: Schnier, Joachim B., Nishi, Kayoko, Harley, William R., Gorin, Fredric A.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996278/
https://ncbi.nlm.nih.gov/pubmed/18404250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-008-9591-8
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