Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: role of macrophages.

In newborn rats the levels of nerve growth factor (NGF) mRNA (mRNANGF) and NGF receptor mRNA (mRNA(rec)) in the sciatic nerve were 10 and 120 times higher, respectively, than in adult animals. mRNA(rec) levels decreased steadily from birth, approaching adult levels by the third postnatal week, where...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Heumann, R, Lindholm, D, Bandtlow, C, Meyer, M, Radeke, M J, Misko, T P, Shooter, E, Thoenen, H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299621/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2825206/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.23.8735
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