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A Physiologic and Pharmacological Basis for Implementation of Incretin Hormones in the Treatment of Type 2 Diabetes Mellitus

Progressive deterioration of β-cell function is a hallmark of type 2 diabetes mellitus (DM). Together with increasing insulin resistance in peripheral tissues (in both the liver and the skeletal muscle), the inability of pancreatic insulin secretion to manage fasting and postprandial glucose levels...

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Autore principale: Freeman, Jeffrey S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mayo Foundation for Medical Education and Research 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996163/
https://ncbi.nlm.nih.gov/pubmed/21106868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4065/mcp.2010.0467
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