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Metallated Aziridines for Cross-Coupling with Aryl and Alkenyl Halides via Palladium Catalysis

[Image: see text] The palladium catalyzed coupling of an aziridinylzinc chloride intermediate with alkenyl and aryl halides has been demonstrated. The method provides products with retention of aziridine stereochemistry. The utility of the coupling procedure is illustrated in the synthesis of struct...

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Detalhes bibliográficos
Main Authors: Nelson, John M., Vedejs, Edwin
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996137/
https://ncbi.nlm.nih.gov/pubmed/20945857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol101904a
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