Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients.

Deposition of amyloid in pancreatic islets is a common feature in human type 2 diabetic subjects but because of its insolubility and low tissue concentrations, the structure of its monomer has not been determined. We describe a peptide, of calculated molecular mass 3905 Da, that was a major protein...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Cooper, G J, Willis, A C, Clark, A, Turner, R C, Sim, R B, Reid, K B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299599/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3317417/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.23.8628
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