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The role of pannexin hemichannels in the anoxic depolarization of hippocampal pyramidal cells
Neuronal gap junctional hemichannels, composed of pannexin-1 subunits, have been suggested to play a crucial role in epilepsy and brain ischaemia. After a few minutes of anoxia or ischaemia, neurons in brain slices show a rapid depolarization to ∼−20 mV, called the anoxic depolarization. Glutamate r...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2995884/ https://ncbi.nlm.nih.gov/pubmed/20940167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awq284 |
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