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IGF-1 Synergizes with BMP7-Mediated Anabolism In Bovine Intervertebral Disc Cells

OBJECTIVE: To assess therapeutic benefits for intervertebral disc matrix repair and regeneration, the potential synergism of IGF-1 and BMP7 on bovine spine discs were evaluated, and molecular/cellular mechanisms were elucidated. METHODS: Bovine nucleus pulposus (NP) cells were treated with BMP7 and...

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Detalhes bibliográficos
Main Authors: Kim, Jaesung, Ellman, Michael B, An, Howard S, van Wijnen, Andre J., Borgia, Jeffrey A, Im, Hee-Jeong
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995823/
https://ncbi.nlm.nih.gov/pubmed/20812336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27733
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