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Iron regulates ferritin mRNA translation through a segment of its 5' untranslated region.
In previous studies, we showed that acute administration of iron to intact rats or to rat hepatoma cells in culture induces synthesis of the iron-storage protein ferritin by activating translation of inactive cytoplasmic ferritin mRNAs for both the heavy (H) and the light (L) subunits. In the course...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1987
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299567/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3479802/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.23.8478 |
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