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Mechanism by Which Metformin Reduces Glucose Production in Type 2 Diabetes

To examine the mechanism by which metformin lowers endogenous glucose production in type 2 diabetic patients, we studied seven type 2 diabetic subjects, with fasting hyperglycemia (15.5 ± 1.3 mmol/l), before and after 3 months of metformin treatment. Seven healthy subjects, matched for sex, age, and...

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Detalhes bibliográficos
Main Authors: Hundal, Ripudaman S., Krssak, Martin, Dufour, Sylvie, Laurent, Didier, Lebon, Vincent, Chandramouli, Visvanathan, Inzucchi, Silvio E., Schumann, William C., Petersen, Kitt F., Landau, Bernard R., Shulman, Gerald I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995498/
https://ncbi.nlm.nih.gov/pubmed/11118008
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