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Tamoxifen decreases ovarian follicular loss from experimental toxicant DMBA and chemotherapy agents cyclophosphamide and doxorubicin in the rat

INTRODUCTION: We serendipitously observed a protective effect of tamoxifen against depletion of ovarian follicles by 7,12-dimethylbenzanthracene (DMBA), a chemical carcinogen, during a cancer prevention study. Such ovarian protection is being sought as an alternative approach to fertility preservati...

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Detalhes bibliográficos
Main Authors: Ting, Alison Y., Petroff, Brian K.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995431/
https://ncbi.nlm.nih.gov/pubmed/20711751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-010-9463-y
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