Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells

Mammalian PKD (protein kinase D) isoforms have been implicated in the regulation of diverse biological processes in response to diacylglycerol and PKC (protein kinase C) signalling. To compare the functions of PKD1 and PKD2 in vivo, we generated mice deficient in either PKD1 or PKD2 enzymatic activi...

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Bibliographic Details
Main Authors: Matthews, Sharon A., Navarro, Maria N., Sinclair, Linda V., Emslie, Elizabeth, Feijoo-Carnero, Carmen, Cantrell, Doreen A.
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995424/
https://ncbi.nlm.nih.gov/pubmed/20819079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101188
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