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Afferent baroreflex failure in familial dysautonomia

BACKGROUND: Familial dysautonomia (FD) is due to a genetic deficiency of the protein IKAP, which affects development of peripheral neurons. Patients with FD display complex abnormalities of the baroreflex of unknown cause. METHODS: To test the hypothesis that the autonomic phenotype of FD is due to...

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Autori principali: Norcliffe-Kaufmann, Lucy, Axelrod, Felicia, Kaufmann, Horacio
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Academy of Neurology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995385/
https://ncbi.nlm.nih.gov/pubmed/21098405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181feb283
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