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Azidothymidine: crystal structure and possible functional role of the azido group.

The crystal and molecular structures of the anti-acquired immunodeficiency syndrome agent 3'-azido-3'-deoxythymidine (AZT) have been determined by x-ray diffraction. There are two crystallographically independent AZT molecules in the crystal asymmetric unit; they have similar conformations and diffe...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Camerman, A, Mastropaolo, D, Camerman, N
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1987
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299517/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2446321/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.23.8239
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