The RSC chromatin-remodeling complex influences mitotic exit and adaptation to the spindle assembly checkpoint by controlling the Cdc14 phosphatase

Upon prolonged activation of the spindle assembly checkpoint, cells escape from mitosis through a mechanism called adaptation or mitotic slippage, which is thought to underlie the resistance of cancer cells to antimitotic drugs. We show that, in budding yeast, this mechanism depends on known essenti...

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Main Authors: Rossio, Valentina, Galati, Elena, Ferrari, Matteo, Pellicioli, Achille, Sutani, Takashi, Shirahige, Katsuhiko, Lucchini, Giovanna, Piatti, Simonetta
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2010
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995168/
https://ncbi.nlm.nih.gov/pubmed/21098112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201007025
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