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Targeting the jagged/notch pathway: a new treatment for fibrosis?
There is no treatment for fibrotic disease. TGFβ is known to promote fibrogenesis in vivo and in vitro, however, development of anti-fibrotic strategies targeting the TGFβ axis is problematic owing to the pleitropic nature of TGFβ action. Two recent papers (Kavian et al. 2010; Nyhan et al. 2010) sug...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Springer Netherlands
2010
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2995132/ https://ncbi.nlm.nih.gov/pubmed/21234126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-010-0101-3 |
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