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The role of transcription factories-mediated interchromosomal contacts in the organization of nuclear architecture

Using numerical simulations, we investigate the underlying physical effects responsible for the overall organization of chromosomal territories in interphase nuclei. In particular, we address the following three questions: (i) why are chromosomal territories with relatively high transcriptional acti...

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Autori principali: Dorier, Julien, Stasiak, Andrzej
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995080/
https://ncbi.nlm.nih.gov/pubmed/20675721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq666
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