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The role of transcription factories-mediated interchromosomal contacts in the organization of nuclear architecture

Using numerical simulations, we investigate the underlying physical effects responsible for the overall organization of chromosomal territories in interphase nuclei. In particular, we address the following three questions: (i) why are chromosomal territories with relatively high transcriptional acti...

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Hlavní autoři: Dorier, Julien, Stasiak, Andrzej
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995080/
https://ncbi.nlm.nih.gov/pubmed/20675721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq666
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