GAM/ZFp/ZNF512B is central to a gene sensor circuitry involving cell-cycle regulators, TGFβ effectors, Drosha and microRNAs with opposite oncogenic potentials

MicroRNAs (miRNAs) are small regulatory RNAs targeting multiple effectors of cell homeostasis and development, whose malfunctions are associated with major pathologies such as cancer. Herein we show that GAM/ZFp/ZNF512B works within an intricate gene regulatory network involving cell-cycle regulator...

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Sonraí Bibleagrafaíochta
Main Authors: Tili, Esmerina, Michaille, Jean-Jacques, Liu, Chang-Gong, Alder, Hansjuerg, Taccioli, Cristian, Volinia, Stefano, Calin, George A., Croce, Carlo M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2010
Ábhair:
RNA
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995059/
https://ncbi.nlm.nih.gov/pubmed/20639536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq637
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