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GPR30 co-localizes with cholinergic neurons in the basal forebrain and enhances potassium-stimulated acetylcholine release in the hippocampus

GPR30 is a novel, membrane-bound, G protein-coupled estrogen receptor (Filardo et al., 2002; Prossnitz et al., 2008). We hypothesize that GPR30 may mediate effects of estradiol (E2) on basal forebrain cholinergic neurons and cognitive performance. Recently we showed that G-1, a selective GPR30 agoni...

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Hlavní autoři: Hammond, R., Nelson, D., Gibbs, R.B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994977/
https://ncbi.nlm.nih.gov/pubmed/20696528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2010.07.007
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