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Targeting the Midgut Secreted PpChit1 Reduces Leishmania major Development in Its Natural Vector, the Sand Fly Phlebotomus papatasi

BACKGROUND: During its developmental cycle within the sand fly vector, Leishmania must survive an early proteolytic attack, escape the peritrophic matrix, and then adhere to the midgut epithelia in order to prevent excretion with remnants of the blood meal. These three steps are critical for the est...

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מידע ביבליוגרפי
Main Authors: Coutinho-Abreu, Iliano V., Sharma, Narinder K., Robles-Murguia, Maricela, Ramalho-Ortigao, Marcelo
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994919/
https://ncbi.nlm.nih.gov/pubmed/21152058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000901
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